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Targeted next-generation sequencing approach for CCR5, CXCR4 and IFNAR1 genes in HIV+ participants: Association of single nucleotide polymorphisms with CD4+ T cell count and HIV replication in patients receiving antiretroviral therapy

2024-09-10

Abstract excerpt

HIV, which causes acquired immune deficiency syndrome, invades the host cell via the CD4 receptor and CCR5 or CXCR4 co-receptors. Interferons induced early in HIV infection induce an antiviral defense mechanism through IFNAR signaling. Our study aimed to examine the relationship between CCR5 , CXCR4 , and IFNAR1 gene variations as a risk factor in HIV (+) patients and their response to their clinical parameters...

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Literature Corpus work: b146a606-d622-5b59-a2c1-a1464d3ca852
DOI: 10.22541/au.172597150.07494032/v1

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Targeted next-generation sequencing approach for CCR5, CXCR4 and IFNAR1 genes in HIV+ participants: Association of single nucleotide polymorphisms with CD4+ T cell count and HIV replication in patients receiving antiretroviral therapyDOI 10.22541/au.172597150.07494032/v1Read

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