Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GATA3frameshift mutation promotes tumor growth in human luminal breast cancer cells and induces transcriptional changes seen in primaryGATA3mutant breast cancers

20 Oct 2017

Abstract excerpt

// John P. Gustin 1 , Jernelle Miller 1 , Mina Farag 1 , D. Marc Rosen 1 , Matthew Thomas 1 , Robert B. Scharpf 1 and Josh Lauring 1 1 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA Correspondence to: Josh Lauring, email: jlauring@jhmi.edu Keywords: GATA3, mutation, breast cancer, luminal Received: October 05, 2017 Accepted: October 10, 2017 Published: October 20, 2017 ABSTRACT The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced biosensing and bioanalysis techniques
Share to Cancer Diagnosis and Treatment
Share to Metastasis and carcinoma case studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29262572
DOI: 10.18632/oncotarget.21910

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GATA3frameshift mutation promotes tumor growth in human luminal breast cancer cells and induces transcriptional changes seen in primaryGATA3mutant breast cancersPMID 29262572Read ↗

GATA3 in Breast Cancer: Tumor Suppressor or Oncogene?Semantic proximity Read ↗

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driverSemantic proximity Read ↗

Shift in GATA3 functions, and GATA3 mutations, control progression and clinical presentation in breast cancer.Semantic proximity Read ↗

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver.Semantic proximity Read ↗

Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug SensitivitySemantic proximity Read ↗

The Significance and Therapeutic Potential of GATA3 Expression and Mutation in Breast Cancer: A Systematic Review.Semantic proximity Read ↗

GATA3 mutations define a unique subtype of luminal-like breast cancer with improved survival.Semantic proximity Read ↗

Mutant GATA3 Actively Promotes the Growth of Normal and Malignant Mammary Cells.Semantic proximity Read ↗

Mutation of GATA3 in human breast tumors.Semantic proximity Read ↗

Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover.Semantic proximity Read ↗

GATA3-extension mutants rewire lineage identity in luminal breast cancerSemantic proximity Read ↗

GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional networkSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.