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Article

The Significance and Therapeutic Potential of GATA3 Expression and Mutation in Breast Cancer: A Systematic Review.

Medicinal research reviews - 1 Nov 2015

Du Feng, Yuan Peng, Wang Teng, Zhao Jiuda, Zhao Zitong, Luo Yang, Xu Binghe

Abstract excerpt

GATA3 is a critical transcription factor in the development of various human systems. The notion that GATA3 expression is required for the differentiation and maintenance of normal breast tissue has been well established. Recently, GATA3 is found to actively participate in the multistep process leading breast cancer pathogenesis, including tumorigenesis, tumor differentiation, epithelial mesenchymal transition,...

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Identifiers

PMID: 26313026
DOI: 10.1002/med.21362

Genes

GATA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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