Article
GATA3 mutations define a unique subtype of luminal-like breast cancer with improved survival.
Cancer - 1 May 2014
Jiang Yi-Zhou, Yu Ke-Da, Zuo Wen-Jia, Peng Wen-Ting, Shao Zhi-Ming
Abstract excerpt
BACKGROUND: The GATA3 gene (GATA-binding protein 3) is one of the most frequently mutated genes in breast cancer. The objective of the current study was to determine the clinicopathologic characteristics of patients with breast cancer harboring GATA3 mutations. METHODS: The authors examined the somatic mutation status of GATA3 and performed survival analysis in The Cancer Genome Atlas (TCGA) cohort (n=934) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
