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Article

Molecular Prerequisites for Diminished Cold Sensitivity in Ground Squirrels and Hamsters.

Cell reports - 19 Dec 2017

Matos-Cruz Vanessa, Schneider Eve R, Mastrotto Marco, Merriman Dana K, Bagriantsev Sviatoslav N, Gracheva Elena O

Abstract excerpt

Thirteen-lined ground squirrels and Syrian hamsters are known for their ability to withstand cold during hibernation. We found that hibernators exhibit cold tolerance even in the active state. Imaging and electrophysiology of squirrel somatosensory neurons reveal a decrease in cold sensitivity of TRPM8-expressing cells. Characterization of squirrel and hamster TRPM8 showed that the channels are chemically...

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Source

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Identifiers

PMID: 29262313
DOI: 10.1016/j.celrep.2017.11.083
PMCID: PMC5741102

Genes

TRPM8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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