Article
The cellular code for mammalian thermosensation.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Mar 2013
Pogorzala Leah A, Mishra Santosh K, Hoon Mark A
Abstract excerpt
Mammalian somatosenory neurons respond to thermal stimuli and allow animals to reliably discriminate hot from cold and to select their preferred environments. Previously, we generated mice that are completely insensitive to temperatures from noxious cold to painful heat (-5 to 55°C) by ablating several different classes of nociceptor early in development. In the present study, we have adopted a selective ablation...
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