Article

Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death

2024-07-26

Abstract excerpt

<h4>Summary</h4> Cells must adapt to environmental changes to maintain homeostasis. One of the most striking environmental adaptations is entry into hibernation during which core body temperature can decrease from 37°C to as low at 4°C. How mammalian cells, which evolved to optimally function within a narrow range of temperatures, adapt to this profound decrease in temperature remains poorly understood. In this s...

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Literature Corpus work: 90ac1611-9917-525a-9f01-9afdf331833b
DOI: 10.1101/2024.07.25.605098

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