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Article

Investigation of BRAF V600E detection approaches in papillary thyroid carcinoma.

Pathology, research and practice - 1 Feb 2018

Chen Dan, Qi Wenjing, Zhang Pengxin, Zhang Yunkun, Liu Ye, Guan Hongwei, Wang Lifen

Abstract excerpt

OBJECTIVE: The detection of BRAF V600E mutation in papillary thyroid carcinoma (PTC) may be helpful to offer diagnostic confirmation. Additionally, such detection may provide a targeted therapeutic approach for the radioactive iodine resistant patients to predict adverse outcomes. To compare the results of immunohistochemistry (IHC) method using the anti-BRAF V600E (VE1) antibody with the Quantitative real-time...

Topics

Carcinoma, Papillary
DNA, Neoplasm
Humans
Immunohistochemistry
Mutation
Neoplasm Metastasis
Proto-Oncogene Proteins B-raf
Thyroid Cancer, Papillary
Thyroid Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29254799
DOI: 10.1016/j.prp.2017.09.001

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-29254799-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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