Article
Specific immunohistochemical detection of the BRAF V600E mutation in primary and metastatic papillary thyroid carcinoma.
Experimental and molecular pathology - 1 Feb 2016
Zhu Xiaoli, Luo Yanli, Bai Qianming, Lu Yongming, Lu Yiqiong, Wu Lijing, Zhou Xiaoyan
Abstract excerpt
PURPOSE: To evaluate the clinical value of immunohistochemistry (IHC) using anti-BRAF V600E antibody (clone VE1) for specific detection of the BRAF V600E mutant protein in formalin-fixed paraffin-embedded papillary thyroid carcinoma (PTC) specimens. METHODS: A total of 118 PTC cases and 116 control cases processed between January 2008 and June 2010 were selected and created tissue microarrays (TMAs) for the...
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