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Article

Comparison of Immunohistochemistry and Direct Sequencing Methods for Identification of the BRAFV600E Mutation in Papillary Thyroid Carcinoma.

Annals of surgical oncology - 1 Jun 2018

Kim Jong-Kyu, Seong Chan Yong, Bae In Eui, Yi Jin Wook, Yu Hyeong Won, Kim Su-Jin, Won Jae-Kyung, Chai Young Jun, Choi June Young, Lee Kyu Eun

Abstract excerpt

BACKGROUND: BRAFV600E mutation is the most common somatic variant in papillary thyroid carcinoma (PTC) and is associated with aggressive prognostic factors. The conventional detection method for BRAF mutations is polymerase chain reaction followed by Sanger sequencing. Recently, an immunohistochemistry (IHC) method using a BRAFV600E-specific antibody (VE1) has been developed and widely adopted in the clinics;...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29611028
DOI: 10.1245/s10434-018-6460-3

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Comparison of Immunohistochemistry and Direct Sequencing Methods for Identification of the BRAFV600E Mutation in Papillary Thyroid Carcinoma.PMID 29611028Read ↗

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VE1 immunohistochemical detection of the BRAF V600E mutation in thyroid carcinoma: a review of its usefulness and limitations.Semantic proximity Read ↗

Diagnostic Value of Immunohistochemistry for the Detection of the <i> BRAF <sup>V600E</sup> </i> Mutation in Papillary Thyroid Carcinoma: Comparative Analysis with Three DNA-Based AssaysSemantic proximity Read ↗

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Comparison of diagnostic methods for the detection of a BRAF mutation in papillary thyroid cancerSemantic proximity Read ↗

Evaluation of molecular diagnostic approaches for the detection of BRAF p.V600E mutations in papillary thyroid cancer: Clinical implications.Semantic proximity Read ↗

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