Article
Immunohistochemistry as an accurate tool for evaluating BRAF-V600E mutation in 130 samples of papillary thyroid cancer.
Surgery - 1 Apr 2017
Abd Elmageed Zakaria Y, Sholl Andrew B, Tsumagari Koji, Al-Qurayshi Zaid, Basolo Fulvio, Moroz Krzysztof, Boulares A Hamid, Friedlander Paul, Miccoli Paulo, Kandil Emad
Abstract excerpt
BACKGROUND: BRAFV600E mutation has been investigated by immunohistochemistry and has shown high sensitivity and specificity. We aim to investigate the accuracy of immunohistochemistry versus molecular testing of BRAFV600E in papillary thyroid cancer using a large number of polymerase chain reaction-positive BRAFV600E papillary thyroid cancer tissues. METHODS: We stained 130 formalin-fixed papillary thyroid cancer...
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