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Article

Clinical utility of immunohistochemistry for the detection of the BRAF v600e mutation in papillary thyroid carcinoma.

Surgery - 1 Dec 2013

Zagzag Jonathan, Pollack Aron, Dultz Linda, Dhar Shumon, Ogilvie Jennifer B, Heller Keith S, Deng Fang-Ming, Patel Kepal N

Abstract excerpt

BACKGROUND: BRAF V600E mutation is the most common genetic alteration in papillary thyroid cancer (PTC). We used a mutation-specific antibody for immunohistochemical (IHC) detection of the BRAF V600E mutation and correlated expression with clinicopathologic features. The study was designed to validate the accuracy and determine the clinical importance of IHC detection of the BRAF V600E mutation in PTC. METHODS:...

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Source

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Identifiers

PMID: 23931769
DOI: 10.1016/j.surg.2013.06.020
PMCID: PMC4100700

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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