Article
The relation between BRAFV600E mutation and clinicopathological characteristics of papillary thyroid cancer.
Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina - 1 Feb 2020
Celik Mehmet, Bulbul Buket Yılmaz, Ayturk Semra, Durmus Yusuf, Gurkan Hakan, Can Nuray, Tastekin Ebru, Ustun Funda, Sezer Atakan, Guldiken Sibel
Abstract excerpt
Aim BRAF mutation inhibits many tumour suppressor genes, increases pro-angiogenic molecules and reduces radioactive iodine uptake of tumour in papillary thyroid cancer (PTC), giving it more aggressive clinical characteristics. In this study, we aimed to evaluate the effect of BRAF V600E mutation on the clinicopathological features in patients with PTC. Methods The laboratory and clinical findings of 256 PTC...
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