Article
Inflammatory chemokine eotaxin-1 is correlated with age in heroin dependent patients under methadone maintenance therapy.
Drug and alcohol dependence - 1 Feb 2018
Kuo Hsiang-Wei, Liu Tung-Hsia, Tsou Hsiao-Hui, Hsu Ya-Ting, Wang Sheng-Chang, Fang Chiu-Ping, Liu Chia-Chen, Chen Andrew C H, Liu Yu-Li
Abstract excerpt
BACKGROUND: Degeneration of central neurons and fibers has been observed in postmortem brains of heroin dependent patients. However, there are no biomarkers to predict the severity of neurodegeneration related to heroin dependence. A correlation has been reported between inflammatory C-C motif chemokine ligand 11 (CCL11, or eotaxin-1) and neurodegeneration in Alzheimer's disease. METHODS: Three-hundred-forty-four...
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