Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential Regulation of Neurotoxin in HIV Clades: Role of Cocaine and Methamphetamine

1 Jul 2012

Abstract excerpt

Studies have demonstrated that infection with HIV-1 (subtypes) clades might differentially contribute to HIV- 1-associated neuro cognitive disorder (HAND). Substance abuse and illicit drugs such as cocaine and methamphetamine (METH) are also known to play a role in neuronal impairments. Neurotoxin quinolinic acid (QUIN) and arachidonic acid (AA) metabolites are regulators of central nervous system (CNS)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Tryptophan and brain disorders
Share to HIV Research and Treatment
Share to Treatment of Major Depression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22591367
DOI: 10.2174/157016212802138742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential Regulation of Neurotoxin in HIV Clades: Role of Cocaine and MethamphetaminePMID 22591367Read ↗

The neuropathogenesis of HIV-1 infectionSemantic proximity Read ↗

Neurological impact of HIV/AIDS and substance use alters brain function and structureSemantic proximity Read ↗

Epigenetic Alterations in the Brain Associated with HIV-1 Infection and Methamphetamine DependenceSemantic proximity Read ↗

Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microgliaSemantic proximity Read ↗

Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl.Semantic proximity Read ↗

Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategiesSemantic proximity Read ↗

Modulation in the Gene Expression Profile of Astrocytes and Monocytes by HIV-1 Nef VariantsSemantic proximity Read ↗

Methamphetamine activates nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and induces human immunodeficiency virus (HIV) transcription in human microglial cellsSemantic proximity Read ↗

Molecular mechanisms of programmed cell death in methamphetamine-induced neuronal damageSemantic proximity Read ↗

Increased human immunodeficiency virus (HIV) type 1 DNA content and quinolinic acid concentration in brain tissues from patients with HIV encephalopathy.Semantic proximity Read ↗

Short Communication: Methamphetamine Treatment Increases <i>in Vitro</i> and <i>in Vivo</i> HIV ReplicationSemantic proximity Read ↗

Human immunodeficiency virus type 1 clade B and C Tat differentially induce indoleamine 2,3-dioxygenase and serotonin in immature dendritic cells: Implications for neuroAIDSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.