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Article

Predisposition to accelerated Alzheimer-related changes in the brains of human immunodeficiency virus negative opiate abusers.

Brain : a journal of neurology - 1 Dec 2010

Anthony Iain C, Norrby Katherine E, Dingwall Tommy, Carnie Frances W, Millar Tracey, Arango Juan Carlos, Robertson Roy, Bell Jeanne E

Abstract excerpt

Cognitive impairment is a recognized effect of drug misuse, including the use of opiates. The pathological basis for this is unknown but the temporal and frontal cortices have been implicated. We have shown previously that deposits of hyperphosphorylated tau in drug user brains exceed those seen in age-matched controls. The present quantitative study of hyperphosphorylated tau and beta amyloid in drug user brains...

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Identifiers

PMID: 21126996
DOI: 10.1093/brain/awq263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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