Article
Polymorphisms of brain-derived neurotrophic factor associated with heroin dependence.
Neuroscience letters - 20 May 2011
Jia W, Shi J G, Wu B, Ao L, Zhang R, Zhu Y S
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) promotes synaptic remodeling and modulates the function of other neurotransmitters. It also plays a role in the reward response to many drugs, including heroin. To identify genetic variants associated with heroin dependence, we compared four single nucleotide polymorphisms (SNPs, rs13306221, rs6265, rs56164415, and rs16917204) of the BDNF gene in 487 subjects with heroin...
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