Article
Pan-cancer analysis of expressed somatic nucleotide variants in long intergenic non-coding RNA.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2018
Ching Travers, Garmire Lana X
Abstract excerpt
Long intergenic non-coding RNAs have been shown to play important roles in cancer. However, because lincRNAs are a relatively new class of RNAs compared to protein-coding mRNAs, the mutational landscape of lincRNAs has not been as extensively studied. Here we characterize expressed somatic nucleotide variants within lincRNAs using 12 cancer RNA-Seq datasets in TCGA. We build machine-learning models to...
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