Article

RNAIndel: discovering somatic coding indels from tumor RNA-Seq data

2019-01-07

Abstract excerpt

Reliable identification of expressed somatic insertion/deletion (indels) is an unmet demand due to artifacts generated in PCR-based RNA-Seq library preparation and the lack of normal RNA-Seq data, presenting analytical challenges for discovery of somatic indels in tumor trasncriptome. By implementing features characterized by PCR-free whole-genome and whole-exome sequencing into a machine-learning framework, we pr...

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Literature Corpus work: 61ef800b-875c-5e90-a219-cfc1eee0bf54
DOI: 10.1101/512749

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