Article
Integrative analysis reveals clinical phenotypes and oncogenic potentials of long non-coding RNAs across 15 cancer types.
Oncotarget - 7 Jun 2016
Wang Ze-Lin, Li Bin, Piccolo Stephen R, Zhang Xiao-Qin, Li Jun-Hao, Zhou Hui, Yang Jian-Hua, Qu Liang-Hu
Abstract excerpt
Long non-coding RNAs (lncRNAs) have been shown to contribute to tumorigenesis. However, surprisingly little is known about the comprehensive clinical and genomic characterization of lncRNAs across human cancer. In this study, we conducted comprehensive analyses for the expression profile, clinical outcomes, somatic copy number alterations (SCNAs) profile of lncRNAs in ~7000 clinical samples from 15 different...
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