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Article

Genetic bypass of essential RNA repair enzymes in budding yeast.

RNA (New York, N.Y.) - 1 Mar 2018

Cherry Patrick D, White Laura K, York Kerri, Hesselberth Jay R

Abstract excerpt

RNA repair enzymes catalyze rejoining of an RNA molecule after cleavage of phosphodiester linkages. RNA repair in budding yeast is catalyzed by two separate enzymes that process tRNA exons during their splicing and HAC1 mRNA exons during activation of the unfolded protein response (UPR). The RNA ligase Trl1 joins 2',3'-cyclic phosphate and 5'-hydroxyl RNA fragments, creating a phosphodiester linkage with a...

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Source

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Identifiers

PMID: 29212664
DOI: 10.1261/rna.061788.117
PMCID: PMC5824351

Genes

TPT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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