Article
Accumulation of pre-tRNA splicing '2/3' intermediates in a Saccharomyces cerevisiae mutant.
The EMBO journal - 1 Apr 1990
Ho C K, Rauhut R, Vijayraghavan U, Abelson J
Abstract excerpt
In an effort to identify genes involved in the excision of tRNA introns in Saccharomyces cerevisiae, temperature-sensitive mutants were screened for intracellular accumulation of intron-containing tRNA precursors by RNA hybridization analysis. In one mutant, tRNA splicing intermediates consisting of the 5' exon covalently joined to the intron ('2/3' pre-tRNA molecules) were detected in addition to unspliced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
