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Article

Power Analysis for Genetic Association Test (PAGEANT) provides insights to challenges for rare variant association studies.

Bioinformatics (Oxford, England) - 1 May 2018

Derkach Andriy, Zhang Haoyu, Chatterjee Nilanjan

Abstract excerpt

Motivation: Genome-wide association studies are now shifting focus from analysis of common to rare variants. As power for association testing for individual rare variants may often be low, various aggregate level association tests have been proposed to detect genetic loci. Typically, power calculations for such tests require specification of large number of parameters, including effect sizes and allele...

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Identifiers

PMID: 29194474
DOI: 10.1093/bioinformatics/btx770
PMCID: PMC5925788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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