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Article

Recommended joint and meta-analysis strategies for case-control association testing of single low-count variants.

Genetic epidemiology - 1 Sept 2013

Ma Clement, Blackwell Tom, Boehnke Michael, Scott Laura J

Abstract excerpt

In genome-wide association studies of binary traits, investigators typically use logistic regression to test common variants for disease association within studies, and combine association results across studies using meta-analysis. For common variants, logistic regression tests are well calibrated, and meta-analysis of study-specific association results is only slightly less powerful than joint analysis of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23788246
DOI: 10.1002/gepi.21742
PMCID: PMC4049324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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