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Article

Power loss due to testing association between covariate-adjusted traits and genetic variants.

Genetic epidemiology - 1 Sept 2020

Yajnik Pranav, Boehnke Michael

Abstract excerpt

Multiple linear regression is commonly used to test for association between genetic variants and continuous traits and estimate genetic effect sizes. Confounding variables are controlled for by including them as additional covariates. An alternative technique that is increasingly used is to regress out covariates from the raw trait and then perform regression analysis with only the genetic variants included as...

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Identifiers

PMID: 32511788
DOI: 10.1002/gepi.22325
PMCID: PMC7610149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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