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Article

Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI.

Journal of computer-aided molecular design - 1 Dec 2017

Alba Josephine, Marcaida Maria Jose, Prieto Jesus, Montoya Guillermo, Molina Rafael, D'Abramo Marco

Abstract excerpt

I-DmoI, from the hyperthermophilic archaeon Desulfurococcus mobilis, belongs to the LAGLIDADG homing endonuclease protein family. Its members are highly specific enzymes capable of recognizing long DNA target sequences, thus providing potential tools for genome manipulation. Working towards this particular application, many efforts have been made to generate mesophilic variants of I-DmoI that function at lower...

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PMID: 29177929
DOI: 10.1007/s10822-017-0087-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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