Article
The diagnostic role of PTEN and ARID1A in serous effusions.
Virchows Archiv : an international journal of pathology - 1 Mar 2018
Davidson Ben, Pinamonti Maurizio, Cuevas Dolors, Holth Arild, Zeppa Pio, Hager Thomas, Wohlschlaeger Jeremias, Tötsch Martin
Abstract excerpt
The aim of this study was to analyze the diagnostic role of PTEN and ARID1A in effusion cytology. Effusions (n = 279), consisting of 226 carcinomas (70 ovarian, 64 breast, 36 lung, and 15 uterine corpus carcinomas; 41 carcinomas of other origin) and 53 malignant mesotheliomas, were analyzed for PTEN and ARID1A expression using immunohistochemistry. PTEN was preserved in 166 (59%) tumors, partially lost in 38...
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