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Somatic PTEN and ARID1A loss and endometriosis disease burden: a longitudinal study

19 Dec 2024

Abstract excerpt

STUDY QUESTION: Is there an association between the somatic loss of PTEN (phosphatase and tensin homolog) and ARID1A (AT-rich interaction domain 1A) and endometriosis disease severity and worse clinical outcomes? SUMMARY ANSWER: Somatic PTEN loss in endometriosis epithelium was associated with greater disease burden and subsequent surgical complexity. WHAT IS KNOWN ALREADY: Somatic cancer-driver mutations...

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Chromatin Remodeling and Cancer
Dermatological and Skeletal Disorders
Endometriosis Research and Treatment

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39701665
DOI: 10.1093/humrep/deae269

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