Article
Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervix.
Cancer letters - 8 Jul 2004
Minaguchi Takeo, Yoshikawa Hiroyuki, Nakagawa Shunsuke, Yasugi Toshiharu, Yano Tetsu, Iwase Haruko, Mizutani Katsumi, Shiromizu Kenji, Ohmi Kazuo, Watanabe Yoh, Noda Kiichiro, Nishiu Mieko, Nakamura Yusuke, Taketani Yuji
Abstract excerpt
Serous, mucinous, endometrioid, and clear cell adenocarcinomas arise from reproductive organs of mullerian origin. Although the mutation of PTEN, a tumor suppressor, is known to be involved in tumorigenesis of endometrioid adenocarcinomas of the endometrium and ovary, the role of PTEN alteration in endometrioid adenocarcinoma of the cervix remains to be investigated. To elucidate the molecular pathogenesis of...
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