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Article

Loss of phosphatase and tensin homolog protein expression is an independent poor prognostic marker in lung adenocarcinoma.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2012

Yanagawa Naoki, Leduc Charles, Kohler Derek, Saieg Mauro A, John Thomas, Sykes Jenna, Yoshimoto Maisa, Pintilie Melania, Squire Jeremy, Shepherd Frances A, Tsao Ming-Sound

Abstract excerpt

INTRODUCTION: Phosphatase and tensin homolog (PTEN) has been established as a tumor suppressor gene with an important role in regulating the phosphatidylinositol-3-kinase/AKT antiapoptotic and survival pathway. The prognostic role of PTEN in non-small-cell lung carcinoma has not been evaluated co...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22982652
DOI: 10.1097/JTO.0b013e3182641d4f

Genes

PTEN
EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22982652-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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