Article
Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas.
The Journal of pathology - 1 Jul 2011
Wiegand Kimberly C, Lee Anna F, Al-Agha Osama M, Chow Christine, Kalloger Steve E, Scott David W, Steidl Christian, Wiseman Sam M, Gascoyne Randy D, Gilks Blake, Huntsman David G
Abstract excerpt
Mutation of the ARID1A gene and loss of the corresponding protein BAF250a has recently been described as a frequent event in clear cell and endometrioid carcinomas of the ovary. To determine whether BAF250a loss is common in other malignancies, immunohistochemistry (IHC) for BAF250a was performed on tissue microarrays (TMAs) in more than 3000 cancers, including carcinomas of breast, lung, thyroid, endometrium,...
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