Article
ARID1A is a useful marker of malignancy in peritoneal washings for endometrial carcinoma.
Cancer cytopathology - 1 Apr 2015
Nagymanyoki Zoltan, Mutter George L, Hornick Jason L, Cibas Edmund S
Abstract excerpt
BACKGROUND: ARID1A (AT-rich interactive domain 1A gene) has recently been identified as a novel tumor suppressor gene and one of the driver genes in endometrial carcinogenesis. Approximately 30% to 40% of endometrial carcinomas harbor mutations in the ARID1A gene, which results in complete loss of ARID1A protein expression. Although ARID1A aberrations are not restricted to endometrial cancer, the authors...
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