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Article

The peptidylglycine-α-amidating monooxygenase (PAM) gene rs13175330 A>G polymorphism is associated with hypertension in a Korean population.

Human genomics - 21 Nov 2017

Yoo Hye Jin, Kim Minjoo, Kim Minkyung, Chae Jey Sook, Lee Sang-Hyun, Lee Jong Ho

Abstract excerpt

BACKGROUND: Peptidylglycine-α-amidating monooxygenase (PAM) may play a role in the secretion of atrial natriuretic peptide (ANP), which is a hormone involved in the maintenance of blood pressure (BP). The objective of the present study was to determine whether PAM is a novel candidate gene for hypertension (HTN). RESULTS: A total of 2153 Korean participants with normotension and HTN were included. Genotype data...

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Source

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Identifiers

PMID: 29162152
DOI: 10.1186/s40246-017-0125-3
PMCID: PMC5696732

Genes

PAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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