Article
Association of the AGXT2 V140I polymorphism with risk for coronary heart disease in a Chinese population.
Journal of atherosclerosis and thrombosis - 1 Jan 2014
Zhou Ji-Peng, Bai Yong-Ping, Hu Xiao-Lei, Kuang Da-Bin, Shi Rui-Zheng, Xiong Yan, Zhang Wei, Xia Jian, Chen Bi-Lian, Yang Tian-Lun, Chen Xiao-Ping
Abstract excerpt
AIM: Asymmetric dimethylarginine (ADMA) is a nitric oxide synthase (NOS) inhibitor that decreases NO production and promotes the development of cardiovascular diseases. Alanine-glyoxylate aminotransferase 2 (AGXT2) plays an important role in ADMA metabolism. This study was designed to explore the association of the AGXT2 V140I (rs37369 G>A) polymorphism with risk for coronary heart disease (CHD) in a Chinese...
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