Article
Single nucleotide polymorphisms of the angiotensin-converting enzyme (ACE) gene are associated with essential hypertension and increased ACE enzyme levels in Mexican individuals.
PloS one - 1 Jan 2013
Martínez-Rodríguez Nancy, Posadas-Romero Carlos, Villarreal-Molina Teresa, Vallejo Maite, Del-Valle-Mondragón Leonardo, Ramírez-Bello Julian, Valladares Adan, Cruz-López Miguel, Vargas-Alarcón Gilberto
Abstract excerpt
AIM: To explore the role of the ACE gene polymorphisms in the risk of essential hypertension in Mexican Mestizo individuals and evaluate the correlation between these polymorphisms and the serum ACE levels. METHODS: Nine ACE gene polymorphisms were genotyped by 5' exonuclease TaqMan genotyping assays and polymerase chain reaction (PCR) in 239 hypertensive and 371 non- hypertensive Mexican individuals. Haplotypes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.