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Type 2 Diabetes Mellitus pathogenesis and role of Peptidylglycine Alpha-Amidating Monooxygenase (PAM) Gene elaboration by In-silico Analysis

2025-10-14

Abstract excerpt

Type 2 Diabetes Mellitus (T2DM) is caused by pancreatic beta cell failure and alpha cell dysfunction that are central to this disease pathophysiology. For T2DM, the Peptidylglycine Alpha-Amidating Monooxygenase (PAM) gene has susceptible locus as identified by Genome-wide association studies (GWAS) though underlying molecular mechanisms remained poorly characterised. This study have explored comprehensive in-silic...

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Literature Corpus work
7bdd827f-28ae-54d4-a07b-0425a183e124
DOI
10.1101/2025.10.12.681891
Open publication

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Type 2 Diabetes Mellitus pathogenesis and role of Peptidylglycine Alpha-Amidating Monooxygenase (PAM) Gene elaboration by In-silico AnalysisDOI 10.1101/2025.10.12.681891
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