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Article

Adaptive SNP-Set Association Testing in Generalized Linear Mixed Models with Application to Family Studies.

Behavior genetics - 1 Jan 2018

Park Jun Young, Wu Chong, Basu Saonli, McGue Matt, Pan Wei

Abstract excerpt

In genome-wide association studies (GWAS), it has been increasingly recognized that, as a complementary approach to standard single SNP analyses, it may be beneficial to analyze a group of functionally related SNPs together. Among the existent population-based SNP-set association tests, two adaptive tests, the aSPU test and the aSPUpath test, offer a powerful and general approach at the gene- and pathway-levels...

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PMID: 29150721
DOI: 10.1007/s10519-017-9883-x
PMCID: PMC5754233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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