Article
Common biological networks underlie genetic risk for alcoholism in African- and European-American populations.
Genes, brain, and behavior - 1 Jul 2013
Kos M Z, Yan J, Dick D M, Agrawal A, Bucholz K K, Rice J P, Johnson E O, Schuckit M, Kuperman S, Kramer J, Goate A M, Tischfield J A, Foroud T, Nurnberger J, Hesselbrock V, Porjesz B, Bierut L J, Edenberg H J, Almasy L
Abstract excerpt
Alcohol dependence (AD) is a heritable substance addiction with adverse physical and psychological consequences, representing a major health and economic burden on societies worldwide. Genes thus far implicated via linkage, candidate gene and genome-wide association studies (GWAS) account for only a small fraction of its overall risk, with effects varying across ethnic groups. Here we investigate the genetic...
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