Article
Powerful and Adaptive Testing for Multi-trait and Multi-SNP Associations with GWAS and Sequencing Data.
Genetics - 1 Jun 2016
Kim Junghi, Zhang Yiwei, Pan Wei
Abstract excerpt
Testing for genetic association with multiple traits has become increasingly important, not only because of its potential to boost statistical power, but also for its direct relevance to applications. For example, there is accumulating evidence showing that some complex neurodegenerative and psychiatric diseases like Alzheimer's disease are due to disrupted brain networks, for which it would be natural to...
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