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Article

Simultaneous selection of multiple important single nucleotide polymorphisms in familial genome wide association studies data.

Scientific reports - 25 May 2023

Majumdar Subhabrata, Basu Saonli, McGue Matt, Chatterjee Snigdhansu

Abstract excerpt

We propose a resampling-based fast variable selection technique for detecting relevant single nucleotide polymorphisms (SNP) in a multi-marker mixed effect model. Due to computational complexity, current practice primarily involves testing the effect of one SNP at a time, commonly termed as 'single SNP association analysis'. Joint modeling of genetic variants within a gene or pathway may have better power to...

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Identifiers

PMID: 37231056
DOI: 10.1038/s41598-023-35379-y
PMCID: PMC10213008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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