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Article

NRP1-positive lung cancer cells possess tumor-initiating properties.

Oncology reports - 1 Jan 2018

Jimenez-Hernandez Luis E, Vazquez-Santillan Karla, Castro-Oropeza Rosario, Martinez-Ruiz Gustavo, Muñoz-Galindo Laura, Gonzalez-Torres Carolina, Cortes-Gonzalez Carlo C, Victoria-Acosta Georgina, Melendez-Zajgla Jorge, Maldonado Vilma

Abstract excerpt

Tumor-initiating cells possess the capacity for self-renewal and to create heterogeneous cell lineages within a tumor. Therefore, the identification and isolation of cancer stem cells is an essential step in the analysis of their biology. The aim of the present study was to determine whether the cell surface protein neuropilin 1 (NRP1) can be used as a biomarker of stem-like cells in lung cancer tumors. For this...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29138851
DOI: 10.3892/or.2017.6089
PMCID: PMC5783600

Genes

NRP1
NANOG
OLFML3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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