Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VEGF-A/Neuropilin 1 Pathway Confers Cancer Stemness via Activating Wnt/β-Catenin Axis in Breast Cancer Cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2017

Zhang Lansheng, Wang Hongmei, Li Caihong, Zhao Yang, Wu Langjie, Du Xiuping, Han Zhengxiang

Abstract excerpt

BACKGROUND/AIMS: Targeting cancer stem cells (CSCs) is emerging as a promising method for cancer treatment. We previously indicated that knockdown of Neuropilin 1(NRP-1) could inhibit breast cancer cell proliferation. Here, we continue exploring the roles and mechanisms of VEGF-A/NRP-1 axis in breast CSCs formation. METHODS: qRT-PCR was used to detect the levels of VEGF-A and NRP-1 in breast cancer sphere cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Doxorubicin
Share to Human Umbilical Vein Endothelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MCF-7 Cells

Share to Neovascularization, Physiologic

Share to Neuropilin-1

Share to Spheroids, Cellular

Share to Transplantation, Heterologous

Share to Wnt3A Protein

Source

Identifiers

PMID: 29179185
DOI: 10.1159/000485455

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VEGF-A/Neuropilin 1 Pathway Confers Cancer Stemness via Activating Wnt/β-Catenin Axis in Breast Cancer Cells.PMID 29179185Read ↗

MicroRNA-1 down-regulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/β-catenin pathway.Semantic proximity Read ↗

MiR-4319 Suppress the Malignancy of Triple-Negative Breast Cancer by Regulating Self-Renewal and Tumorigenesis of Stem CellsSemantic proximity Read ↗

Neuropilin-1 is upregulated by Wnt/β-catenin signaling and is important for mammary stem cellsSemantic proximity Read ↗

The C-X-C Motif Chemokine Ligand 1 Sustains Breast Cancer Stem Cell Self-Renewal and Promotes Tumor Progression and Immune Escape ProgramsSemantic proximity Read ↗

A balanced level of profilin-1 promotes stemness and tumor-initiating potential of breast cancer cellsSemantic proximity Read ↗

VEGF-A acts via neuropilin-1 to enhance epidermal cancer stem cell survival and formation of aggressive and highly vascularized tumorsSemantic proximity Read ↗

NRP1-positive lung cancer cells possess tumor-initiating properties.Semantic proximity Read ↗

USP44+ Cancer Stem Cell Subclones Contribute to Breast Cancer Aggressiveness by Promoting Vasculogenic Mimicry.Semantic proximity Read ↗

Neuropilin-1 Knockout and Rescue Confirms Its Role to Promote Metastasis in MDA-MB-231 Breast Cancer CellsSemantic proximity Read ↗

MicroRNA Regulation of Breast Cancer StemnessSemantic proximity Read ↗

NEDD4 Plays Roles in the Maintenance of Breast Cancer Stem Cell CharacteristicsSemantic proximity Read ↗

HES1 promotes breast cancer stem cells by elevating Slug in triple-negative breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.