Article
Descriptive analysis of tumor cells with stem like phenotypes in metastatic and benign adrenal tumors.
Journal of pediatric surgery - 1 Sept 2015
Jensen Todd, Vadasz Stephanie, Phoenix Kathryn, Claffey Kevin, Parikh Nehal, Finck Christine
Abstract excerpt
BACKGROUND: Neuroblastoma (NB) comprises 7% of all childhood cancers. Here we report a descriptive analysis of key cellular markers that have "stem-like" properties which theoretically represents the self-renewing population of cells responsible for generating new tumor cells. Samples are obtained from freshly isolated tissue from nonmetastatic NB, metastatic NB, benign adrenal adenoma and a ganglioneuroma. In...
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