Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Non-Small Cell Lung Cancer Cells Expressing CD44 Are Enriched for Stem Cell-Like Properties

19 Nov 2010

Abstract excerpt

BACKGROUND: The cancer stem cell theory hypothesizes that cancers are perpetuated by cancer stem cells (CSC) or tumor initiating cells (TIC) possessing self-renewal and other stem cell-like properties while differentiated non-stem/initiating cells have a finite life span. To investigate whether the hypothesis is applicable to lung cancer, identification of lung CSC and demonstration of these capacities is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Research and Disease Studies
Share to Cancer Cells and Metastasis
Share to Hippo pathway signaling and YAP/TAZ

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21124918
DOI: 10.1371/journal.pone.0014062

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Non-Small Cell Lung Cancer Cells Expressing CD44 Are Enriched for Stem Cell-Like PropertiesPMID 21124918Read ↗

Identification and expansion of the tumorigenic lung cancer stem cell population.Semantic proximity Read ↗

Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cellsSemantic proximity Read ↗

CD133 is a temporary marker of cancer stem cells in small cell lung cancer, but not in non-small cell lung cancerSemantic proximity Read ↗

Single-Cell Transcriptomics Unveils the Dedifferentiation Mechanism of Lung Adenocarcinoma Stem CellsSemantic proximity Read ↗

The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy.Semantic proximity Read ↗

Lung cancer stem cells—characteristics, phenotypeSemantic proximity Read ↗

Targeting Lung Cancer Stem Cells: Research and Clinical ImpactsSemantic proximity Read ↗

CD44 and CD24 cannot act as cancer stem cell markers in human lung adenocarcinoma cell line A549Semantic proximity Read ↗

The role of CD133 in the identification and characterisation of tumour-initiating cells in non-small-cell lung cancer☆☆☆Semantic proximity Read ↗

Lung cancer stem cells: Molecular features and therapeutic targetsSemantic proximity Read ↗

Stemness and inducing differentiation of small cell lung cancer NCI-H446 cellsSemantic proximity Read ↗

[Lung adenocarcinoma stem cell phenotypes and their correlation with patient prognosis].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.