Article

Targeting neuropilin-1 and neutralizing interleukin-6 inhibits cancer stem cell formation in bladder cancer cells

2025-11-24

Abstract excerpt

<title>Abstract</title> <p>Background Bladder urothelial carcinoma (BLCA) recurrence is frequently driven by an aggressive tumor microenvironment and the persistence of cancer stem cells (CSCs), both of which contribute to therapeutic resistance and metastasis. Neuropilin-1 (NRP1) is increasingly recognized as a key orchestrator of epithelial-mesenchymal transition (EMT), endowing tumor cells with enhanced chemor...

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Literature Corpus work: 31dda1b0-5c85-512f-92ca-c9224eaea05a
DOI: 10.21203/rs.3.rs-8052232/v1

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