Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The rs2292239 polymorphism in ERBB3 gene is associated with risk for type 1 diabetes mellitus in a Brazilian population.

Gene - 20 Feb 2018

Lemos Natália Emerim, Dieter Cristine, Dorfman Luiza Emy, Assmann Taís Silveira, Duarte Guilherme Coutinho Kullmann, Canani Luis Henrique, Bauer Andrea Carla, Crispim Daisy

Abstract excerpt

The Erb-b2 receptor tyrosine kinase 3 (ERBB3) belongs to a family of epidermal growth factor receptors of protein tyrosine kinases, and regulates cell survival, differentiation and proliferation in several cell types. Previous studies have suggested that ERBB3 contributes to T1DM pathogenesis by modulating antigen presenting cell function, autoimmunity and cytokine-induced beta-cell apoptosis. Accordingly, some...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Gene Frequency

Share to Genome-Wide Association Study

Share to Introns

Share to Receptor, ErbB-3

Source

Identifiers

PMID: 29109006
DOI: 10.1016/j.gene.2017.11.009

Genes

ERBB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The rs2292239 polymorphism in ERBB3 gene is associated with risk for type 1 diabetes mellitus in a Brazilian population.PMID 29109006Read ↗

The rs705708 A allele of the ERBB3 gene is associated with lower prevalence of diabetic retinopathy and arterial hypertension and with improved renal function in type 1 diabetic patients.Semantic proximity Read ↗

The genetic and regulatory architecture of ERBB3-type 1 diabetes susceptibility locus.Semantic proximity Read ↗

Genetically dependent ERBB3 expression modulates antigen presenting cell function and type 1 diabetes risk.Semantic proximity Read ↗

[Association of the polymorphisms of the ERBB3 and SH2B3 genes with type 1 diabetes].Semantic proximity Read ↗

Association Between ERBB2 and ERBB3 Polymorphisms and Dyslipidaemia and Serum Lipid Levels in a Chinese Population.Semantic proximity Read ↗

Evidence for two independent associations with type 1 diabetes at the 12q13 locus.Semantic proximity Read ↗

Association of β3-adrenergic receptor rs4994 polymorphisms with the risk of type 2 diabetes: A systematic review and meta-analysis.Semantic proximity Read ↗

Trp homozygotes at codon 64 of ADRB3 gene are protected against the risk of type 2 diabetes in the Kashmiri population.Semantic proximity Read ↗

Association of TCR/CD3, PTPN22, CD28 and ZAP70 gene polymorphisms with type 1 diabetes risk in Tunisian population: family based association study.Semantic proximity Read ↗

Non-HLA Risk Loci ERBB3/IKZF4 and ERBB2/IKZF3/GSDMB/ORMDL3 Interact to Influence Progression of Autoimmunity in Relatives of T1D Patients.Semantic proximity Read ↗

Polymorphisms of ERBB2 and breast cancer risk: a meta-analysis of 26 studies involving 35,088 subjects.Semantic proximity Read ↗

Genetic variation at ERBB3/IKZF4 and sexual dimorphism in epitope spreading in single autoantibody-positive relatives.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.