Trp homozygotes at codon 64 of ADRB3 gene are protected against the risk of type 2 diabetes in the Kashmiri population.

doi:10.1089/gtmb.2013.0297

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Article

Trp homozygotes at codon 64 of ADRB3 gene are protected against the risk of type 2 diabetes in the Kashmiri population.

Genetic testing and molecular biomarkers - 1 Oct 2013

Hameed Iqra, Masoodi Shariq R, Afroze Dil, Naykoo Niyaz A, Bhat Riyaz A, Ganai Bashir A

Abstract excerpt

The prevalence of type 2 diabetes mellitus has reached epidemic proportions worldwide. Type 2 diabetes is a consequence of complex interactions among multiple genetic variants and environmental risk factors. Polymorphisms in various candidate genes confer susceptibility to diabetes. This study was undertaken to analyse a single nucleotide polymorphism Trp64Arg (C↔T) in the ADRB3 gene and elucidate its effects on...

Topics

Adult
Alleles
Amino Acid Substitution
Body Mass Index
Case-Control Studies
Codon
Diabetes Mellitus, Type 2
Dyslipidemias
Female
Genetic Predisposition to Disease
Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

India

Male

Middle Aged

Mutation, Missense

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 23968135
DOI: 10.1089/gtmb.2013.0297

Genes

ADRB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Trp homozygotes at codon 64 of ADRB3 gene are protected against the risk of type 2 diabetes in the Kashmiri population.PMID 23968135Read ↗

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Meta-analysis of the association between the Trp64Arg polymorphism of the beta-3 adrenergic receptor and susceptibility to gestational diabetes mellitus.Semantic proximity Read ↗

The Trp64Arg polymorphism of the beta3-adrenergic receptor gene is associated with hypertension in men with type 2 diabetes mellitus.Semantic proximity Read ↗

Effect of the combination of the variants -75G/A APOA1 and Trp64Arg ADRB3 on the risk of type 2 diabetes (DM2).Semantic proximity Read ↗

The mutation of Trp64Arg in β3-adrenoreceptor-encoding gene is significantly associated with increased hypertension risk and elevated blood pressure: a meta-analysis.Semantic proximity Read ↗

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