Article
Genetically dependent ERBB3 expression modulates antigen presenting cell function and type 1 diabetes risk.
PloS one - 26 Jul 2010
Wang Hongjie, Jin Yulan, Reddy M V Prasad Linga, Podolsky Robert, Liu Siyang, Yang Ping, Bode Bruce, Reed John Chip, Steed R Dennis, Anderson Stephen W, Steed Leigh, Hopkins Diane, Huang Yihua, She Jin-Xiong
Abstract excerpt
Type 1 diabetes (T1D) is an autoimmune disease resulting from the complex interaction between multiple susceptibility genes, environmental factors and the immune system. Over 40 T1D susceptibility regions have been suggested by recent genome-wide association studies; however, the specific genes and their role in the disease remain elusive. The objective of this study is to identify the susceptibility gene(s) in...
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