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Article

A novel experimental model for human mixed acinar-ductal pancreatic cancer.

Carcinogenesis - 9 Feb 2018

Doiron Bruno, DeFronzo Ralph A

Abstract excerpt

Pancreatic cancer has remained refractory to treatment. In large part, this results from the lack of an animal model that mimics pancreatic cancer in man. We describe a novel experimental model of pancreatic cancer that shares the genetic background, histologic features and natural history of human mixed acinar-ductal carcinoma. Adult wild-type mice received an injection into the pancreatic duct of lentivirus...

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Source

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Identifiers

PMID: 29106450
DOI: 10.1093/carcin/bgx119
PMCID: PMC5862347

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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