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Article

Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas.

Carcinogenesis - 1 Dec 2006

Ueda Shinobu, Fukamachi Katsumi, Matsuoka Yoichiro, Takasuka Nobuo, Takeshita Fumitaka, Naito Akihiro, Iigo Masaaki, Alexander David B, Moore Malcolm A, Saito Izumu, Ochiya Takahiro, Tsuda Hiroyuki

Abstract excerpt

Pancreatic ductal adenocarcinoma is one of the most debilitating malignancies in humans. Currently, radiation and chemotherapy are ineffective, with median survival times after treatment of <12 months. Animal models that reflect the human condition and can be used to explore screening and therapeutic approaches are clearly desirable. One feature of human pancreatic adenocarcinoma is an exceedingly high frequency...

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Identifiers

PMID: 16774944
DOI: 10.1093/carcin/bgl090

Genes

EGF
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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